What is Zyban

Zyban is a brand name for the generic drug Bupropion hydrochloride. It is a non-tricyclic anti-depressant medication used to facilitate smoking cessation. Through this prescription drug, a person’s craving for smoking will be reduced as well as the effects of withdrawal. The action of this medication in regards to smoking cessation is still not fully understood. However, it is recognized that neurotransmitters, which transmit messages between the nerve cells in the brain are affected by bupropion.

Common Side Effects

Zyban consumption can cause to have adverse effects to some people. The most common Zyban side effects that can be mild to some or severe to others are:

• headache
• nausea
• drowsiness
• dizziness
• nervousness
• anxiety
• dry mouth
• stuffy nose
• stomach pain
• diarrhea
• constipation
• vomiting
• appetite changes
• increased sweating
• weight changes
• trouble sleeping

Aside from the mentioned side effects, there are also zyban side effects on the different organs and systems of the body. One of the most affected body systems by this drug is the nervous system. The most frequent side effects reported are headache, migraine, dizziness, insomnia, somnolence, thinking abnormality, sleep abnormalities, impaired sleep quality, tremor, dysphoria, paresthesia, decreased memory, disturbed memory, sedation, akathisia, sensory disturbance, dyarthria, myoclonus, central nervous system stimulation, and seizure.

Another system the drug can have adverse effects on is the gastrointestinal system. Here, the possible side effects of the use of Zyban are nausea, constipation, diarrhea, dry mouth, anorexia, bloating, abdominal cramps, vomiting, abdominal pain, dysphagia, dyspepsia, taste perversion, and increase in appetite.

Moreover, the genitourinary system can also be affected by Zyban. The observed side effects in the sexual organs are: vaginal hemorrhage, pelvic infection, ovarian infection, vaginitis, testicular swelling, menstrual irregularities, painful erection, dyspareunia, prostate disorder, gynecomastia, libido changes, abnormal ejaculation, and impotence. For the urinary system, the side effects include urinary frequency, urinary tract infection, dysuria, enuresis, polyuria, nocturia, glycosuria, urinary incontinence, and urinary retention.

Serious Side Effects

Zyban can also affect the cardiovascular system. The adverse Zyban side effects effects could be the following: cardiac arrhythmias, palpitations, tachycardia, hypotension, hypertension, edema, syncope, chest pain, vasodilation, phlebitis, myocardial infarction, stroke, electrocardiogram abnormalities. There are also infrequent incidences of bradycardia, extrasystoles, and complete atrioventricular block.

Use of Zyban has also reported skin and dermatologic reactions. The most common of them is urticaria. Also included as the frequent side effect of this medicine are hives, rashes, sweating, dry skin, pallor, and flushing. Side effects like hormone level changes and inappropriate anti-diuretic hormone can also happen in the endocrine system. Zyban has metabolic side effects as well that includes weight gain, weight loss, and electrolyte imbalances such as hyperglycemia, hyponatremia, and hypoglycemia.

The musculoskeletal system is also involved in the adverse effects of Zyban. These side effects are musculoskeletal chest pain, muscle rigidity, muscle weakness, leg cramps, and rhabdomyolysis. Also, the liver can be affected. The conditions like abnormal liver function tests, jaundice, hepatitis, and hepatic damage can be produce as side effects of consumption of Bupropion hydrochloride.

Hematologic side effects can also occur like anemia, leucopenia, thrombocytopenia, pancytopenia, leukocytosis, lymphadenopathy, eosinophilia, and ecchymosis. The respiratory system can be affected as well. The side effects can include cough, dyspnea, epistaxis, bronchitis, bronchospasm, pneumonia, and pulmonary embolism.

Side effects on the eyes can occur with the use of Zyban. These side effects are dry eye, blurred vision, diplopia, increased intraocular pressure, and mydriasis. This anti-depressant can affect the psychiatric or mental health of a person. The effects could be anxiety, agitation, irritability, depression, hypomania, hallucinations, euphoria, manic reaction, aggression, delusions, suicidal ideation, psychosis, and emotional lability among others.

Though Zyban is known to help a person in smoking cessation, it has still lots of side effects waiting to be discovered. It is important to take this medication with a doctor’s prescription. Seeking medical help is the best way if ever there is an unusual Zyban side effects or condition with the use of this drug.

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