What is Mirtazapine
Mirtazapine is a drug used to treat depression and sometimes anxiety. It is a tetracyclic anti-depressant, which is also used as an appetite stimulant, anti-emetic, and as a hypnotic drug. This medication acts in the central nervous system by increasing the activity of certain chemicals inside the brain. The brand names of Mirtazapine are Avanza, Remeron, and Zispin among others.
Mirtazapine Side Effects
The most common Mirtazapine side effects that may develop in a patient taking are abnormal thinking, constipation, weight gain, increased appetite, drowsiness, dry mouth, weakness, flu symptoms, and abnormal dreams. These common Mirtazapine side effects can be ignored by some can be very incommodious to others.
Mirtazapine can have side effects on almost all body systems. In the nervous system, the side effects that may develop in a patient taking the said medication are local or generalized paresthesia, numbness, anesthesia, and swelling in the mouth. Other effects also include reduction in REM sleep, headache, somnolence, dizziness, abnormal dreams, insomnia, confusion, abnormal thinking, sleep abnormalities, and tremors. There are also rare cases of seizures, akathisia, mania, and transient ischemic attack.
Common Mirtazapine Drug Side Effects
Side effects can also be noted in the gastrointestinal system. The conditions that can be experienced by a person are constipation, diarrhea, nausea, headache, vomiting, dry mouth, increased appetite, anorexia, colitis, glossitis, and cholecystitis. Moreover, there are also metabolic side effects with the intake of Mirtazapine. The side effects that may occur are increased non-fasting triglyceride, weight gain, peripheral edema, weight loss, and thirst.
In addition to the body systems previously mentioned, musculoskeletal system can also be affected. The patients consuming the drug can develop arthralgia, myasthenia, and myalgia. These conditions can occur within 2 to 22 days of treatment, but disappears after discontinuation of the medication. The only side effect of Mirtazapine that is observed in the respiratory system is dyspnea.
Hepatic side effects can also be experienced with Mirtazapine consumption. These include elevated liver enzymes thrice its normal values especially in ALT. However, there are no clinical signs and symptoms presenting hepatic dysfunction in the reported cases of elevated liver enzymes. The values on the liver function test were also restored to normal levels 2 months after discontinuing the medication.
Serious Possible Mirtazapine Side Effects
In the cardiovascular system, the possible side effects are angina pectoris, vasodilation, ventricular systoles, hypertension, bradycardia, palpiation, tachycardia, postular hypotension, electrocardiogram changes and chest pain. Hematologic side effects can also occur with Mirtazapine. The side effects are the following: leukopenia, lympadenopathy, ecchymosis, petechiae, lymphocytosis, anemia, pancytopenia, and thrombocytopenia. There are also rare cases that developed coagulopathy, neutropenia, and agranulocytosis.
Furthermore, patients taking the medication can experience rash, dry skin, acne, alopecia, and pruritus. There are also rare incidences of dermatologic side effects such as bullous dermatitis, toxic necrolysis, erythema multiforme, and Stevens-Johnson syndrome. Side effects in the eyes can also occur with Mirtazapine. These are eye pain, conjunctivitis, glaucoma, abnormality of accommodation, lacrimation, and palinopsia.
Lastly is the genitourinary system. In this system the possible side effects of Mirtazapine include urinary tract infection, urinary frequency, cystitis, vaginitis, polyuria, urinary incontinence, impotence, hematuris, and kidney calculus.
If with intake of Mirtazapine, any of the following severe side effects are experienced, it is essential to seek medical attention immediately: mouth sores; red, swollen, blistered, or peeling skin; symptoms of infection (sore throat, fever, chills,); severe headache or dizziness; exaggerated feeling of well-being; sluggishness; aggressiveness; impulsiveness; irritability; panic attacks; suicidal thoughts or actions; worsening of depression; restlessness; and seizures. Most of all if there is an experience of difficulty of breathing; a feeling of tightness in the chest; swelling in the face, mouth, lips, tongue; itchiness; appearance of hives and rashes in the body, consult a doctor immediately because these are signs of sever allergic reaction.
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Mirtazapine Side Effects
What is Mirtazapine
Mirtazapine is a drug used to treat depression and sometimes anxiety. It is a tetracyclic anti-depressant, which is also used as an appetite stimulant, anti-emetic, and as a hypnotic drug. This medication acts in the central nervous system by increasing the activity of certain chemicals inside the brain. The brand names of Mirtazapine are Avanza, Remeron, and Zispin among others.
Mirtazapine Side Effects
The most common Mirtazapine side effects that may develop in a patient taking are abnormal thinking, constipation, weight gain, increased appetite, drowsiness, dry mouth, weakness, flu symptoms, and abnormal dreams. These common Mirtazapine side effects can be ignored by some can be very incommodious to others.
Mirtazapine can have side effects on almost all body systems. In the nervous system, the side effects that may develop in a patient taking the said medication are local or generalized paresthesia, numbness, anesthesia, and swelling in the mouth. Other effects also include reduction in REM sleep, headache, somnolence, dizziness, abnormal dreams, insomnia, confusion, abnormal thinking, sleep abnormalities, and tremors. There are also rare cases of seizures, akathisia, mania, and transient ischemic attack.
Common Mirtazapine Drug Side Effects
Side effects can also be noted in the gastrointestinal system. The conditions that can be experienced by a person are constipation, diarrhea, nausea, headache, vomiting, dry mouth, increased appetite, anorexia, colitis, glossitis, and cholecystitis. Moreover, there are also metabolic side effects with the intake of Mirtazapine. The side effects that may occur are increased non-fasting triglyceride, weight gain, peripheral edema, weight loss, and thirst.
In addition to the body systems previously mentioned, musculoskeletal system can also be affected. The patients consuming the drug can develop arthralgia, myasthenia, and myalgia. These conditions can occur within 2 to 22 days of treatment, but disappears after discontinuation of the medication. The only side effect of Mirtazapine that is observed in the respiratory system is dyspnea.
Hepatic side effects can also be experienced with Mirtazapine consumption. These include elevated liver enzymes thrice its normal values especially in ALT. However, there are no clinical signs and symptoms presenting hepatic dysfunction in the reported cases of elevated liver enzymes. The values on the liver function test were also restored to normal levels 2 months after discontinuing the medication.
Serious Possible Mirtazapine Side Effects
In the cardiovascular system, the possible side effects are angina pectoris, vasodilation, ventricular systoles, hypertension, bradycardia, palpiation, tachycardia, postular hypotension, electrocardiogram changes and chest pain. Hematologic side effects can also occur with Mirtazapine. The side effects are the following: leukopenia, lympadenopathy, ecchymosis, petechiae, lymphocytosis, anemia, pancytopenia, and thrombocytopenia. There are also rare cases that developed coagulopathy, neutropenia, and agranulocytosis.
Furthermore, patients taking the medication can experience rash, dry skin, acne, alopecia, and pruritus. There are also rare incidences of dermatologic side effects such as bullous dermatitis, toxic necrolysis, erythema multiforme, and Stevens-Johnson syndrome. Side effects in the eyes can also occur with Mirtazapine. These are eye pain, conjunctivitis, glaucoma, abnormality of accommodation, lacrimation, and palinopsia.
Lastly is the genitourinary system. In this system the possible side effects of Mirtazapine include urinary tract infection, urinary frequency, cystitis, vaginitis, polyuria, urinary incontinence, impotence, hematuris, and kidney calculus.
If with intake of Mirtazapine, any of the following severe side effects are experienced, it is essential to seek medical attention immediately: mouth sores; red, swollen, blistered, or peeling skin; symptoms of infection (sore throat, fever, chills,); severe headache or dizziness; exaggerated feeling of well-being; sluggishness; aggressiveness; impulsiveness; irritability; panic attacks; suicidal thoughts or actions; worsening of depression; restlessness; and seizures. Most of all if there is an experience of difficulty of breathing; a feeling of tightness in the chest; swelling in the face, mouth, lips, tongue; itchiness; appearance of hives and rashes in the body, consult a doctor immediately because these are signs of sever allergic reaction.
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